PPY antibody

Catalog No. ABIN7670710

This anti-PPY antibody is a Rat Polyclonal antibody detecting PPY in ELISA. Suitable for Human.

Quick Overview for PPY antibody (ABIN7670710)

Target: PPY (Pancreatic Polypeptide (PPY))

Reactivity: Human

Host: Rat

Clonality: Polyclonal

Conjugate: This PPY antibody is un-conjugated

Application: ELISA

Product Details anti-PPY Antibody

Purpose: Pancreatic polypeptide/PPY Polyclonal Antibody

Purification: Antigen Affinity Purification

Immunogen: Recombinant Human Pancreatic polypeptide/PPY protein expressed by E.coli

Isotype: IgG

Application Details

Application Notes: ELISA Capture 2-8 μg/mL,ELISA Detector 0.1-0.4 μg/mL

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: Sterile PBS , pH 7.4

Preservative: Without preservative

Handling Advice: Avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C Valid for 1 month or -20°C Valid for 12 months

Expiry Date: 12 months

Target Details for PPY

Target: PPY (Pancreatic Polypeptide (PPY))

Alternative Name: Pancreatic polypeptide/PPY

Background: Pancreatic poLypeptide prohormone,PH,Pancreatic poLypeptide Y,Pancreatic poLypeptide,Pancreatic icosapeptide,PPY,PNP,Pancreatic polypeptide (PP),36-amino acid peptide,may function as an important feedback inhibitor of pancreatic secretion after a meal. It arises from both islet and acinar cells of the pancreas. Release of PP by a meal,primarily protein,occurs in a biphasic manner. PP is a negative regulator of energy homeostasis that suppresses food intake and lowers body weight. Similar to other gastrointestinal-derived peptides,PP also modulates gastrointestinal motility and may be involved in the regulation of anxiety. PP,a robust anorexigenic hormone,effectively modulates food intake and energy homeostasis,thus potentially aiding anti-obesity therapeutics. PP is produced in pancreatic islets of Langerhans and released into the circulation after ingestion of a meal. Peripherally administered PP suppresses food intake and gastric emptying. On the other hand,central administration of PP elicits food intake and gastric emptying.

UniProt: P01298

Pathways: Feeding Behaviour